Nephrogenous Predictors of Early Preeclampsia

The review of modern scientific researches summarizes the studies of nephrogenous preeclampsia genesis, in particular – the studies of modern biomarkers considering the pathogenesis of kidney damage. We have reviewed the renal markers with respective mechanisms and time terms associated with various levels of nephron damage. Severity and specificity of renal damage and its sensitivity during preeclampsia screening were also reviewed. Attention has been paid to use of preeclampsia screening in clinical practice during all trimesters of pregnancy.

Keywords: preeclampsia, screening, renal biomarkers, gelatinase-associated lipocalin, CystatinC, рodocyturia.